Research

Design of Fab-based chimeric antibodies against Bothrops asper toxins

Abstract

Snakebite is one of the world’s most neglected tropical diseases, with an estimated 5 million bites per year, resulting in about 125.000 deaths. The only current treatment for snakebite envenoming is antiserum derived from the blood of immunized mammals(typically horses). These antisera are expensive to produce and carry a high risk of causing hyper-allergic reactions in human recipients due to their heterologous origin. Here we report the discovery of chimeric scFvs against Bothrops asper toxins.

Info

Conference Poster, 2016

UN SDG Classification
DK Main Research Area

    Science/Technology

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