Discovery of human antibodies against sea snake venom phospholipase A2s from Aipysurus laevis
Abstract
Snakebite is one of the world’s most neglected tropical diseases, with an estimated 5.5 million bites peryear, resulting in 125.000 deaths. The only current treatment for snakebite envenoming is antiserumderived from the blood of immunized mammals (typically horses). These antisera are expensive toproduce and carry a high risk of causing hyper-allergic reactions in human recipients due to theirheterologous origin. Here we report the discovery of human scFvs against Aipysurus laevis toxins.
Info
Conference Poster, 2016
UN SDG Classification
DK Main Research Area
Science/Technology
